Ting Peng

The paper presents scMOCHA, a tool to analyze mtDNA heteroplasmy from scRNA-seq data, revealing cell type-specific mtDNA variants and disease mechanisms in hematopoietic cells.

This study uses multimodal imaging and transcriptomics to show increased reactive oxygen species activity in myocardial tissue and systemic organs after myocardial infarction, with associated gene expression changes.

This paper develops properly-polarized trophoblast stem cell-derived organoids that mimic the in vivo placental structure, enabling better modeling of placental development and maternal-fetal interactions.