Deep-learning-based interpolation of longitudinal microbiome data powers biologically informative discovery
Yixiang Qu, Ruiqi Lyu, Duan Wang, Yifan Dai, Alistair Turcan, Shilin Yu, Jialiu Xie, Jeffrey M. Roach, Catherine A. Butler, Pew‐Thian Yap, Hongtu Zhu B, Stuart G. Dashper, Apoena Aguiar Ribeiro, Didong Li, Kimon Divaris, Di Wu
This paper introduces BGOB, a deep learning framework for longitudinal microbiome interpolation, improving analysis of microbial community trajectories and revealing disease-related associations.
bioRxiv · Feb 17, 2025 · PreprintMicrobiology