An oncolytic herpesvirus expressing a CXCR4 antagonist interferes with Glioblastoma cells stemness features and migration.
Paolo D’Arrigo, Dubois Maxime, Judit Sánchez Gil, Cédric Lassence, Brouwers Benoit, Arnaud Lombard, Bernard Rogister, Virginie Neirinckx, Lebrun Marielle, Catherine Sadzot‐Delvaux
This study shows an oncolytic herpesvirus expressing a CXCR4 antagonist reduces GSC stemness and migration in vitro and in a mouse model.
bioRxiv · May 21, 2025 · PreprintCancer Biology