The Protein Tyrosine Phosphatase CD45 promotes PMN Transepithelial Migration, Antimicrobial Function and Colonic Mucosal Repair
Jael Miranda, Dylan Fink, Zachary S. Wilson, Roland Hilgarth, Asma Nusrat, Charles A. Parkos, Jennifer Catherine Brazil
This study shows CD45 promotes PMN transepithelial migration, antimicrobial function, and colonic mucosal repair by regulating CD11b/CD18 and Lyn.
JCI Insight · Jun 23, 2026Peer-reviewedImmunology