Distinct energetic blueprints diversify function of conserved protein folds
Malcolm L. Wells, Chenlin Lu, Daniel Sultanov, Kyle C. Weber, Erin Ahern, Zhen Gong, E Chen, Anum Azam Glasgow
The paper decodes energetic blueprints of conserved protein folds to explain functional diversity and enables engineered transcription factors with ligand-driven responses.
Nature Chemistry · Jun 5, 2026Peer-reviewedBiophysics