Time-resolved proteomic profiling of the ciliary Hedgehog response reveals that GPR161 and PKA undergo regulated co-exit from cilia
E. A. May, M. Kalocsay, I. Galtier D'Auriac, S. P. Gygi, M. V. Nachury, D. U. Mick
The paper uses proximity labeling and mass spectrometry to profile ciliary proteome changes during Hedgehog signaling, identifying new proteins involved in ciliary exit and signaling regulation.
bioRxiv · Jul 29, 2020Cell Biology