The AMPK activator A-769662 inhibits human TASK3 potassium channels in an AMPK-independent manner
E. A. Said, R. W. Lewis, M. L. Dallas, F. A. Ross, a. m. evans
This study shows that A-769662 inhibits human TASK-3 potassium channels independently of AMPK activity, contradicting previous hypotheses about AMPK's role in TASK-3 regulation.
bioRxiv · May 24, 2022 · PreprintPharmacology & Toxicology