Author

A. M. Evans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

S. MacMillan· 3 shared A. D. Mahmoud· 2 shared B. Viollet· 2 shared M. Foretz· 2 shared M. L. Dallas· 2 shared P. Kumar· 2 shared A. Holmes· 1 shared A. P. Holmes· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPhysiology

S. MacMillan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

AMPK deficiency in smooth muscles causes persistent pulmonary hypertension after birth and premature death

J. Moral-Sanz, S. A. Lewis, S. MacMillan, M. Meloni, H. McClafferty, B. Viollet, M. Foretz, J. del-Pozo, A. M. Evans

This study shows that AMPK-1/2 deficiency in smooth muscles leads to persistent pulmonary hypertension and premature death in mice, with no systemic vasculopathy.

bioRxiv · Jun 8, 2022 · PreprintPathology

The AMPK activator A-769662 inhibits human TASK3 potassium channels in an AMPK-independent manner

E. A. Said, R. W. Lewis, M. L. Dallas, F. A. Ross, a. m. evans

This study shows that A-769662 inhibits human TASK-3 potassium channels independently of AMPK activity, contradicting previous hypotheses about AMPK's role in TASK-3 regulation.

bioRxiv · May 24, 2022 · PreprintPharmacology & Toxicology

LKB1 is the gatekeeper of carotid body chemo-sensing and the hypoxic ventilatory response

S. MacMillan, A. P. Holmes, M. L. Dallas, A. D. Mahmoud, M. J. Shipston, D. G. Hardie, P. Kumar, A. M. Evans

This study identifies LKB1 as essential for carotid body chemosensing and the hypoxic ventilatory response, showing divergence in LKB1 and AMPK dependency between the carotid body and the HVR.

bioRxiv · May 24, 2022 · PreprintPhysiology

The hypoxic ventilatory response is facilitated by the activation of Lkb1-AMPK signalling pathways downstream of the carotid bodies

A. M. Evans, A. D. Mahmoud, A. Holmes, S. MacMillan, O. Ogunbayo, C. N. Wyatt, P. Kumar, M. Dallas, B. Viollet, M. Foretz

This study shows that Lkb1-AMPK signaling, but not CaMKK2, is essential for the hypoxic ventilatory response downstream of the carotid bodies.

bioRxiv · Apr 10, 2019 · PreprintPhysiology