E. Ager-Wick

Integrative transcriptomics reveals ectopic lipid homeostasis mechanisms in non-endocrine cells of the teleost pituitary

The paper uses RNA-seq in medaka to show non-endocrine pituitary cells regulate lipid homeostasis during sexual maturation, linking endocrine function to lipid transport gene expression.

Characterization of hormone-producing cell types in the teleost pituitary gland using single-cell RNA-seq

The paper uses single-cell RNA-seq to characterize hormone-producing cell types in the pituitary gland of medaka fish, identifying 15 and 16 distinct cell types in females and males, respectively.

Gonadotropes in medaka grow long extensions with varicosity-like swellings, projecting towards each other and blood vessels.

This study examines the structure and function of gonadotrope extensions in medaka, finding they form networks and may communicate with blood vessels and other gonadotropes.

Gnrh1-induced responses are indirect in female medaka Fsh cells

The paper shows that Gnrh1 affects Fsh release in female medaka indirectly through Lh cells, using electrophysiological and imaging techniques.

Plasticity in medaka gonadotropes via cell proliferation and phenotypic conversion

This study shows that medaka gonadotropes can proliferate and convert phenotypes between Fsh and Lh cells, influenced by estradiol and Gnrh, and lose identity in culture.