P53 is a direct regulator of the immune co-stimulatory molecule CD80
E. Alibo, G. Mollaoglu, M. Dhainaut, R. Zhao, S. Rose, A. Baccarini, R. Parsons, B. D. Brown
This study identifies CD80 as a direct target of P53, showing that P53 loss reduces CD80 expression and impairs T cell priming in colorectal cancer.
bioRxiv · May 24, 2021 · PreprintImmunology