Tumor susceptibility gene-101 regulates glucocorticoid receptor through disorder-mediated allostery
J. T. White, J. Rives, M. E. Tharp, J. O. Wrabl, E. B. Thompson, V. J. Hilser
This study shows TSG101 regulates glucocorticoid receptor by binding its disordered N-terminal domain, enhancing DNA binding and transcriptional activity.
bioRxiv · Feb 2, 2020Biophysics