The acquisition of clinically relevant amoxicillin resistance in Streptococcus pneumoniae requires ordered horizontal gene transfer of four loci
P. S. Gibson, E. Bexkens, S. Zuber, L. Cowley, J.-W. Veening
This study identifies four key genes involved in amoxicillin resistance in Streptococcus pneumoniae and shows that their ordered acquisition via horizontal gene transfer is necessary for resistance development.
bioRxiv · Dec 17, 2021Microbiology