An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies
E. Bjanes, A. Stream, A. B. Janssen, P. S. Gibson, A. M. Bravo, S. Dahesh, J. L. Baker, A. Varble, V. Nizet, J.-W. Veening
This paper develops a doxycycline-inducible CRISPRi system for GAS to enable efficient gene repression and presents a genome browser for GAS genetic features.
bioRxiv · Feb 22, 2024 · PreprintMicrobiology