Anti-NS1 antibodies induced by immunization with dendritic cell targeted hybrid monoclonal antibodies do not induce platelet dysfunction.
E. C. M. Vicentin, K. N. d. S. Amorim, M. M. Yamamoto, H. F. d. S. Souza, D. S. Rosa, A. J. d. S. Goncalves, A. M. d. B. Alves, S. B. Boscardin
This study shows that anti-NS1 antibodies generated by immunizing mice with dendritic cell-targeted NS1 mAbs do not cause platelet dysfunction and provide protection against dengue virus infection.
bioRxiv · Sep 10, 2020 · PreprintImmunology