E. C. Pehrsson

ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3

This study identifies ETS1 as a target of the EWSR1::FLI1 fusion oncoprotein in Ewing sarcoma, showing it regulates TNS3 expression, which promotes cell movement and is linked to metastasis.

Genome-Wide Epigenomic Profiling of Primary Non-Small Cell Lung Cancer Reveals Specific and Recurrent DNA Methylation Alterations in Smoker Versus Never-Smoker Patients

This study identifies recurrent DNA methylation alterations in primary non-small cell lung cancer samples from smokers and never-smokers, highlighting differences in hypomethylation patterns and their association with oncogenes and transcription factor binding motifs.