Author

V. J. Ebegboni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Sundara Rajan· 2 shared T. L. Jones· 2 shared A. D. Tran· 1 shared E. C. Pehrsson· 1 shared J. Loncarek· 1 shared K. R. Ludwig· 1 shared M. J. Kruhlak· 1 shared N. Caplen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

S. Sundara Rajan

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2 papers

Recent·Most cited

EWSR1's visual modalities are defined by its association with nucleic acids and RNA polymerase II

S. Sundara Rajan, V. J. Ebegboni, P. Pichling, K. R. Ludwig, T. L. Jones, R. Chari, A. D. Tran, M. J. Kruhlak, J. Loncarek, N. J. Caplen

This study identifies two visual modalities of EWSR1 in the nucleoplasm, both associated with nascent RNA, and shows EWSR1 foci localize to euchromatin and phosphorylated RNA polymerase II.

Molecular and Cellular Biology · Mar 20, 2024Peer-reviewedCell Biology

ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3

V. J. Ebegboni, T. L. Jones, T. Brownmiller, P. X. Zhao, E. C. Pehrsson, S. Sundara Rajan, N. Caplen

This study identifies ETS1 as a target of the EWSR1::FLI1 fusion oncoprotein in Ewing sarcoma, showing it regulates TNS3 expression, which promotes cell movement and is linked to metastasis.

bioRxiv · Dec 21, 2023Cancer Biology