Behavioral phenotyping of an improved mouse model of Phelan-McDermid Syndrome with a complete deletion of the Shank3 gene
E. Drapeau, M. Riad, Y. Kajiwara, J. D. Buxbaum
This paper describes a new mouse model with a complete Shank3 deletion, showing more severe behavioral deficits than previous models, including anxiety-like behaviors and memory impairments.
bioRxiv · Mar 8, 2018Animal Behavior & Cognition