Single-component optogenetic tools for inducible RhoA GTPase signaling
E. E. Berlew, I. A. Kuznetsov, K. K. Yamada, L. J. Bugaj, J. D. Boerckel, B. Y. Chow
The paper develops optogenetic tools to control RhoA GTPase signaling by directly recruiting effectors to the plasma membrane with light, enabling precise spatiotemporal regulation of actin organization and mechanotransduction.
bioRxiv · Feb 1, 2021Bioengineering