A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer
S. Lovell, L. Zhang, T. Kryza, A. Neodo, N. Bock, E. D. Williams, E. Engelsberger, C. Xu, A. T. Bakker, E. De Vita, M. Maneiro, R. J. Tanaka, C. L. Bevan, J. A. Clements, E. W. Tate
The paper develops activity-based probes to analyze KLK activome dynamics in prostate cancer, revealing KLK14's role in migration and secretion into the bone microenvironment.
bioRxiv · Apr 15, 2021Biochemistry