ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
E. Farmaki, A. Nath, R. Emond, K. L. Karimi, V. K. Grolmusz, P. A. Cosgrove, A. H. Bild
This study shows that combining ONC201/TIC10 with everolimus improves therapeutic response in metastatic ER+ breast cancer by targeting mitochondrial function and oxidative phosphorylation.
eLife · Sep 29, 2023Peer-reviewedCancer Biology