Cancer BiologyeLifePeer-reviewed
ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
E. Farmaki, A. Nath, R. Emond…·A. H. Bild
This study shows that combining ONC201/TIC10 with everolimus improves therapeutic response in metastatic ER+ breast cancer by targeting mitochondrial function and oxidative phosphorylation.
DOI 10.7554/elife.85898