Author

E. Halper-Stromberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Bennett· 2 shared A. Skaist· 2 shared H. Liang· 2 shared J. R. Eshleman· 2 shared K. Bowland· 2 shared N. J. Roberts· 2 shared R. B. Scharpf· 2 shared R. H. Hruban· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Bennett

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers

S. S. K. Teh, K. Bowland, A. Bennett, E. Halper-Stromberg, A. Skaist, J. Tang, F. Cai, A. Macoretta, H. Liang, H. Kamiyama, S. Wheelan, M.-T. Lin, R. H. Hruban, R. B. Scharpf, N. J. Roberts, J. R. Eshleman

This paper demonstrates CRISPR-Cas9 can selectively target somatic mutations in pancreatic cancer by exploiting PAMs in noncoding regions, achieving >80% cell death with minimal off-target effects.

bioRxiv · Apr 15, 2023Cancer Biology

Simultaneous CRISPR-Cas9-induced double strand breaks are lethal in models of pancreatic cancer

S. S. K. Teh, A. Kotwal, A. Bennett, E. Halper-Stromberg, L. Morsberger, S. Zamani, Y. Shi, A. Skaist, Q. Zhu, K. Bowland, H. Liang, R. H. Hruban, C.-F. Hung, R. A. Anders, N. J. Roberts, , J. R. Eshleman

This study shows CRISPR-Cas9-induced DNA double-strand breaks are more cytotoxic to pancreatic cancer cells than radiation-induced breaks, with significant tumor growth inhibition and chromosomal instability.

bioRxiv · Apr 3, 2023Cancer Biology