Group A Streptococcal Collagen-like Protein 1 Restricts Tumor Growth in Murine Pancreatic Adenocarcinoma and Inhibits Cancer-Promoting Neutrophil Extracellular Traps
E. Henderson, A. Ivey, S. J. Choi, S. Santiago, D. McNitt, T. W. Liu, S. Lukomski, B. A. Boone
This study shows that intra-tumoral injection of Group A Streptococcus strains reduces pancreatic tumor growth by inhibiting neutrophil extracellular traps via the Scl1 protein.
bioRxiv · Jan 17, 2024 · PreprintCancer Biology