Author

E. J. Sayers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. T. Jones· 2 shared D. W. Thomas· 2 shared E. L. Ferguson· 2 shared M. Varache· 2 shared S. Rizzo· 2 shared A. Jones· 1 shared A. Mason· 1 shared A. Tonks· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. T. Jones

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2 papers

Recent·Most cited

Modification of the antibiotic, colistin, with dextrin causes enhanced cytotoxicity and triggers apoptosis in myeloid leukemia

S. Rizzo, M. Varache, E. J. Sayers, A. T. Jones, A. Tonks, D. W. Thomas, E. L. Ferguson

This study shows that dextrin-conjugated colistin increases cytotoxicity and induces apoptosis in myeloid leukemia cells compared to free colistin.

International Journal of Nanomedicine · Jun 1, 2024Peer-reviewedPharmacology & Toxicology

Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo.

M. Varache, S. Rizzo, E. J. Sayers, L. Newbury, A. Mason, C.-T. Liao, E. Chiron, N. Bourdiec, A. Jones, D. J. Fraser, P. R. Taylor, A. T. Jones, D. W. Thomas, E. L. Ferguson

bioRxiv · Nov 2, 2023 · PreprintPharmacology & Toxicology