Author

E. K. Mantlo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:variant calling· 2 Organism:human· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

S. Paessler· 4 shared C. Huang· 3 shared N. Bukreyeva· 2 shared A. Evans· 1 shared A. S. Lauring· 1 shared A. S. Monto· 1 shared E. Johnson· 1 shared J. Boutros· 1 shared

Activity by Year

2016-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersMicrobiology

S. Paessler

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5 papers

Recent·Most cited

Lassa virus NP DEDDh 3'-5'exoribonuclease activity is required for optimal viral RNA replication and mutation control.

C. Huang, E. K. Mantlo, S. Paessler, E. K. Mantlo

This study shows that Lassa virus NP ExoN is essential for viral RNA replication and mutation control, highlighting a new role for this protein beyond immune evasion.

bioRxiv · Apr 12, 2023 · PreprintMicrobiology

Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2

E. K. Mantlo, A. Evans, L. Patterson-Fortin, J. Boutros, R. Smith, S. Paessler

This study evaluates the efficacy of CupriDyne, a novel iodine complex, in inactivating SARS-CoV-2, showing 99% reduction in virus titers after 30 minutes.

bioRxiv · May 8, 2020 · PreprintMicrobiology

The IMPDH inhibitor merimepodib suppresses SARS-CoV-2 replication in vitro.

N. Bukreyeva, E. K. Mantlo, R. A. Sattler, C. Huang, S. Paessler, J. Zeldis

This study shows that the IMPDH inhibitor merimepodib suppresses SARS-CoV-2 replication in vitro by reducing viral titers by up to 4 logs after overnight pretreatment.

bioRxiv · Apr 7, 2020 · PreprintMicrobiology

Potent Antiviral Activities of Type I Interferons to SARS-CoV-2 Infection

E. K. Mantlo, N. Bukreyeva, J. Maruyama, S. Paessler, C. Huang

This study shows that Type I interferons significantly reduce SARS-CoV-2 viral titers in Vero cells, with IFN-β being more effective than IFN.

bioRxiv · Apr 2, 2020Microbiology

Vaccination has minimal impact on the intrahost diversity of H3N2 influenza viruses

K. Debbink, J. T. McCrone, J. G. Petrie, R. Truscon, E. Johnson, E. K. Mantlo, A. S. Monto, A. S. Lauring

This study examines the effect of seasonal influenza vaccination on intrahost diversity of H3N2 viruses using whole genome sequencing and finds minimal impact.

bioRxiv · Nov 7, 2016Microbiology