Self-assembled nanoparticles enable delivery of VCP inhibitor, resulting in enhanced photoreceptor protection in retinal explants
M. Sen, M. Al-Amin, E. Kickova, A. Sadeghi, J. Puranen, A. Urtti, P. Caliceti, S. Salmaso, B. Arango-Gonzalez, M. Ueffing
The paper develops nanoformulations of a VCP inhibitor to improve its solubility and delivery, showing enhanced photoreceptor protection in a retinal degeneration model.
bioRxiv · Jun 11, 2021 · PreprintPharmacology & Toxicology