Author

B. Arango-Gonzalez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:rat· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

M. Ueffing· 3 shared M. Sen· 2 shared A. Armento· 1 shared A. Murali· 1 shared A. Sadeghi· 1 shared A. Urtti· 1 shared B. Cao· 1 shared C. A. Ramlogan-Steel· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

M. Ueffing

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FH loss in RPE cells causes retinal degeneration in a human RPE-porcine retinal explant co-culture model

A. Armento, A. Murali, J. Marzi, B. Arango-Gonzalez, E. Kilger, S. J. Clark, K. Schenke-Layland, C. A. Ramlogan-Steel, J. C. Steel, M. Ueffing

This study shows that loss of FH in RPE cells causes retinal degeneration in a co-culture model with porcine retinal explants, with rod cells being the first to degenerate.

bioRxiv · Jul 26, 2021Cell Biology

Pharmacological inhibition of the VCP/proteasome axis rescues photoreceptor degeneration in RHOP23H rat retinal explants

M. Sen, O. Kutsyr, B. Cao, S. Bolz, B. Arango-Gonzalez, M. Ueffing

The paper shows that inhibiting VCP/proteasome activity rescues photoreceptor degeneration in RHOP23H rat retinal explants.

bioRxiv · Jun 14, 2021Cell Biology

Self-assembled nanoparticles enable delivery of VCP inhibitor, resulting in enhanced photoreceptor protection in retinal explants

M. Sen, M. Al-Amin, E. Kickova, A. Sadeghi, J. Puranen, A. Urtti, P. Caliceti, S. Salmaso, B. Arango-Gonzalez, M. Ueffing

The paper develops nanoformulations of a VCP inhibitor to improve its solubility and delivery, showing enhanced photoreceptor protection in a retinal degeneration model.

bioRxiv · Jun 11, 2021 · PreprintPharmacology & Toxicology