Maturation-dependent changes in the structure and seeding capacity of Aβ42 amyloid fibrils
A. M. Miller, S. Chia, E. Klimont, T. Knowles, M. Vendruscolo, F. S. Ruggeri
This study investigates how Aβ42 amyloid fibrils change over time, showing increased length, thickness, and cross-β sheet content, which affects their ability to seed new aggregates.
bioRxiv · Apr 11, 2023 · PreprintBiophysics