Author

E. L. Larson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:comparative / phylogenetic analysis· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. M. Good· 4 shared C. Callahan· 2 shared E. E. K. Kopania· 2 shared K. E. Hunnicutt· 2 shared S. Keeble· 2 shared B. M. Skinner· 1 shared C. C. Rathje· 1 shared E. C. Moore· 1 shared

Activity by Year

2021-2023 · peak 2/yr

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10 top collaborators · 27 mutual co-author links

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4 shared papersEvolutionary Biology

J. M. Good

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4 papers

Recent·Most cited

Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses

K. E. Hunnicutt, C. Callahan, S. Keeble, E. C. Moore, J. M. Good, E. L. Larson

This study compares hybrid male sterility in two rodent crosses, finding stage-dependent misexpression and sex-chromosome overexpression, suggesting distinct mechanisms in dwarf hamsters and house mice.

bioRxiv · Oct 30, 2023Evolutionary Biology

The contribution of sex chromosome conflict to disrupted spermatogenesis in hybrid house mice

E. E. K. Kopania, E. M. Watson, C. C. Rathje, B. M. Skinner, P. J. Ellis, E. L. Larson, J. M. Good

This study investigates how XY chromosome mismatch affects male fertility in hybrid house mice, finding that X chromosome overexpression in spermatids is linked to disrupted meiotic X-inactivation rather than XY gene copy number imbalance.

bioRxiv · Jul 19, 2022Evolutionary Biology

Molecular Evolution across Mouse Spermatogenesis

E. E. K. Kopania, E. L. Larson, C. Callahan, S. Keeble, J. M. Good

The paper investigates molecular evolution across mouse spermatogenesis, finding increased divergence in late stages and differential regulatory mechanisms across cell types.

bioRxiv · Aug 4, 2021Evolutionary Biology

Unraveling patterns of disrupted gene expression across a complex tissue

K. E. Hunnicutt, J. M. Good, E. L. Larson

The paper examines how cellular composition affects gene expression in whole tissue RNASeq, showing that it can skew expression profiles and reduce power to detect differentially expressed genes.

bioRxiv · Jul 8, 2021Evolutionary Biology