J. M. Good

Sperm competition intensity shapes divergence in both sperm morphology and reproductive genes across murine rodents

This study examines how sperm competition intensity influences sperm morphology and reproductive gene evolution across murine rodents, finding that smaller testes correlate with faster molecular evolution due to relaxed selection.

Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses

This study compares hybrid male sterility in two rodent crosses, finding stage-dependent misexpression and sex-chromosome overexpression, suggesting distinct mechanisms in dwarf hamsters and house mice.

The genomic landscape, causes, and consequences of extensive phylogenomic discordance in Old World mice and rats

This study investigates phylogenomic discordance in Old World mice and rats, finding that genetic linkage and selection influence phylogenetic patterns and that assuming a single species tree can lead to errors in detecting positive selection.

A simulation framework for modeling the within-patient evolutionary dynamics of SARS-CoV-2

This study develops a simulation framework to model SARS-CoV-2 evolutionary dynamics within patients, identifying plausible models with severe infection bottlenecks and high rates of deleterious mutations.

Genomic and Radiocarbon Insights into the Mystery of Mouse Mummies on the Summits of >6000 m Andean Volcanoes

The paper reports the discovery of high-altitude mouse mummies and genomic and radiocarbon analyses showing they are recent and genetically similar to lower-altitude populations.

Adaptive structural and functional evolution of the placenta protects fetal growth in high elevation deer mice

This study investigates how high elevation adaptation in deer mice affects placental structure and function to protect fetal growth under hypoxia, identifying conserved genetic pathways and genomic features involved.

The contribution of sex chromosome conflict to disrupted spermatogenesis in hybrid house mice

This study investigates how XY chromosome mismatch affects male fertility in hybrid house mice, finding that X chromosome overexpression in spermatids is linked to disrupted meiotic X-inactivation rather than XY gene copy number imbalance.

Genomic resolution of cryptic species diversity in chipmunks

The paper uses genomic data to identify cryptic species within western chipmunks, revealing two new lineages and a distinct species previously unrecognized as a separate entity.

Stage-specific disruption of X chromosome expression during spermatogenesis in sterile house mouse hybrids

This study investigates X chromosome expression disruption in sterile house mouse hybrids during spermatogenesis, identifying stage-specific gene regulation issues linked to hybrid sterility mechanisms.

Molecular Evolution across Mouse Spermatogenesis

The paper investigates molecular evolution across mouse spermatogenesis, finding increased divergence in late stages and differential regulatory mechanisms across cell types.

Unraveling patterns of disrupted gene expression across a complex tissue

The paper examines how cellular composition affects gene expression in whole tissue RNASeq, showing that it can skew expression profiles and reduce power to detect differentially expressed genes.

X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters

This study identifies X chromosome-driven placental gene expression disruptions in hybrid dwarf hamsters, linking them to hybrid developmental barriers.

The legacy of recurrent introgression during the radiation of hares

This study examines introgression in hares, finding recurrent hybridization across their evolutionary history and identifying shared genetic variation with potential adaptive significance.

Convergent evolution of seasonal camouflage in response to reduced snow cover across the snowshoe hare range

This study investigates how snowshoe hares adapt to reduced snow cover by evolving seasonal camouflage, revealing convergent evolution and the role of allelic dominance in adaptation rates.

The origin and spread of locally adaptive seasonal camouflage in snowshoe hares

The paper investigates the origin and spread of seasonal camouflage in snowshoe hares, finding that hybridization and selection on recessive alleles drove adaptation.