Author

E. Laine

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

G. J. Rocklin· 1 shared J. Chen· 1 shared J. Dauparas· 1 shared J. J. Weinstein· 1 shared K. Tsuboyama· 1 shared N. M. Mangan· 1 shared S. Ovchinnikov· 1 shared Y. Mohseni Behbahani· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

G. J. Rocklin

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1 paper

Recent·Most cited

Mega-scale experimental analysis of protein folding stability in biology and protein design

K. Tsuboyama, J. Dauparas, J. Chen, E. Laine, Y. Mohseni Behbahani, J. J. Weinstein, N. M. Mangan, S. Ovchinnikov, G. J. Rocklin

The paper introduces cDNA display proteolysis to measure protein folding stability for thousands of protein domains, revealing environmental factors, thermodynamic couplings, and evolutionary divergence in amino acid usage.

bioRxiv · Dec 6, 2022Biophysics