ARYL HYDROCARBON RECEPTOR BLOCKS AGING-INDUCED SENESCENCE IN THE LIVER AND FIBROBLAST CELLS
A. Nacarino Palma, E. M. Rico Leo, J. Campisi, A. Ramanathan, J. M. Merino, P. M. Fernandez-Salguero
This study shows that the aryl hydrocarbon receptor (AhR) restricts aging-induced senescence in liver and fibroblast cells, reducing senescence markers and tumor burden.
bioRxiv · Feb 25, 2021Cancer Biology