Cancer BiologybioRxivPreprint
Cancer cells communicate with macrophages to prevent T cell activation during development of cell cycle therapy resistance
J. I. Griffiths, P. A. Cosgrove, E. Medina Castaneda…·A. H. Bild
The paper shows cancer cells in resistant tumors promote immune-suppressive macrophages, reducing T-cell activation, and suggests balancing cell cycle inhibition with immune activation for better therapy.