Author

E. P. Mosher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

N. N. Bumpus· 2 shared B. C. Orsburn· 1 shared C. D. Eberhard· 1 shared J. H. Lee· 1 shared J. M. Berger· 1 shared Y.-S. Lee· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersPharmacology & Toxicology

N. N. Bumpus

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2 papers

Recent·Most cited

Tenofovir Activation is Diminished in the Brain and Liver of Creatine Kinase Brain-Type Knockout Mice

C. D. Eberhard, E. P. Mosher, N. N. Bumpus, B. C. Orsburn

This paper shows that CKB knockout mice have reduced tenofovir activation in brain and liver, with specific mutations impairing CKB's ability to generate the active metabolite TFV-DP.

bioRxiv · Sep 25, 2023Pharmacology & Toxicology

Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites

J. H. Lee, E. P. Mosher, Y.-S. Lee, N. N. Bumpus, J. M. Berger

This study identifies TCA cycle metabolites as regulators of topoisomerase II activity and shows their impact on drug sensitivity in vivo.

bioRxiv · Jan 22, 2021Biochemistry