Author

E. R. Ebel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. Shakya· 1 shared C. N. Nguetse· 1 shared D. A. Petrov· 1 shared D. Enard· 1 shared D. Petrov· 1 shared E. S. Egan· 1 shared F. Reis· 1 shared N. Purington· 1 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

B. Shakya

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Author profile →

3 papers

Recent·Most cited

Shifts in antimalarial drug policy since 2006 have rapidly selected P. falciparum resistance alleles in Angola

E. R. Ebel, F. Reis, D. A. Petrov, S. Beleza

This study examines changes in P. falciparum drug resistance alleles in Angola after a shift to artemisinin combination therapy, finding declining CQ resistance but rising resistance to ACT partner drugs and SP.

bioRxiv · Sep 29, 2020Evolutionary Biology

A common polymorphism in the druggable ion channel PIEZO1 is associated with protection from severe malaria

C. N. Nguetse, N. Purington, B. Shakya, E. R. Ebel, P. G. Kremsner, T. P. Velavan, E. S. Egan

This study identifies a PIEZO1 polymorphism associated with protection from severe malaria in humans, suggesting it as a potential druggable target.

bioRxiv · Jul 3, 2019Microbiology

Pervasive adaptation in Plasmodium-interacting proteins in mammals

E. R. Ebel, N. Telis, S. Venkataram, D. Petrov, D. Enard

This study identifies 410 Plasmodium-interacting proteins in mammals, showing they experience significantly more positive selection than other proteins, linked to immune interactions and pathogen pressure.

bioRxiv · Oct 17, 2016Evolutionary Biology