Loratadine decreases methicillin-resistant Staphylococcus aureus virulence through global hemolysin regulators vraSR and agr.
Chase Dillon, Isabel Marshall, Maggy Henkel, Halie Balogh, Robin Stempel, E. Renee Monge, Gabriel Z. Valenzano, Meghan S. Blackledge, Heather B. Miller
This study shows loratadine reduces MRSA virulence by targeting hemolysin regulators vraSR and agr, decreasing alpha and beta hemolysis in vitro and in cell models.
ACS Omega · Oct 5, 2026Peer-reviewedMicrobiology