Distinct roles of the Na+ binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, GltPh.
F. Valiyaveetil, E. Riederer, P. Moenne-Loccoz
This study investigates the roles of Na+ binding sites in GltPh's transport mechanism, showing Na3 site binding triggers a conformational switch and Na1 site binding partially opens HP2.
bioRxiv · Nov 29, 2021 · PreprintBiophysics