The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state
E. Salido, C. de Medeiros Vieira, J. Verdezoto Mosquera, R. Zade, P. Parikh, S. Suryavanshi, C. L. Miller, V. Lo Sardo
This study shows that the 9p21.3 CAD risk locus drives vascular smooth muscle cells to an osteochondrogenic state through ANRIL expression, leading to arterial calcification.
bioRxiv · May 25, 2024Cell Biology