Author

E. Soutoglou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Meaburn· 2 shared A. Papantonis· 1 shared A. Platania· 1 shared B. Molcrette· 1 shared C. Erb· 1 shared E. Grandgirard· 1 shared G. Monteiro Oliveira· 1 shared J. A. Mitchell· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

K. Meaburn

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2 papers

Recent·Most cited

Inhibition of Topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats

M. Amoiridis, K. Meaburn, J. Verigos, W. H. Gittens, T. Ye, M. J. Neale, E. Soutoglou

This study shows that inhibiting Top2 catalytic activity destabilizes heterochromatin and repetitive DNA, leading to DNA breaks and requiring Ercc1-XPF for resolution.

bioRxiv · Aug 1, 2023 · PreprintCell Biology

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics

A. Platania, C. Erb, M. Barbieri, B. Molcrette, E. Grandgirard, M. A. de Kort, K. Meaburn, T. Taylor, V. M. Shchuka, S. Kocanova, G. Monteiro Oliveira, J. A. Mitchell, E. Soutoglou, T. L. Lenstra, N. Molina, , T. Sexton

The paper investigates how transcription and loop extrusion interact to influence promoter and enhancer dynamics through live tracking and simulations.

bioRxiv · Apr 25, 2023 · PreprintCell Biology