Development of a major histocompatibility complex class II conditional knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves.
E. Ubogu, J. Conner, Y. Wang, D. Yadav, T. Saunders
This paper develops a conditional MHC class II knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves, showing resistance to autoimmune neuropathy despite MHC class II expression.
bioRxiv · Jul 24, 2023Immunology