D. Yadav

A look beyond the QR code of SNARE proteins

The paper investigates the structural arrangement of SNARE proteins in QabcR complexes and shows that structural exchange is tolerated but some non-cognate exchanges lead to imbalances.

Development of a major histocompatibility complex class II conditional knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves.

This paper develops a conditional MHC class II knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves, showing resistance to autoimmune neuropathy despite MHC class II expression.

Proteome-Wide Photo-Crosslinking Enables Residue-Level Visualization of Protein Interaction Networks in vivo

This paper introduces photo-crosslinkers for proteome-wide protein interaction mapping with residue-level resolution, demonstrating their application in E. coli and showing potential for studying low-abundance proteins.

A Newly Identified Class of Protein Misfolding in All-atom Folding Simulations Consistent with Limited Proteolysis Mass Spectrometry

The paper identifies entangled misfolded states in all-atom protein folding simulations that resemble native states and are consistent with mass spectrometry data.

Evolutionary dynamics of Begomoviruses causing Papaya leaf curl disease in India

The paper analyzes genetic diversity and evolutionary dynamics of Begomoviruses causing papaya leaf curl disease in India, finding that mutation drives diversification more than recombination.

Ectopic overexpression of abiotic stress-induced rice annexin, OsAnn5 potentiates tolerance to abiotic stresses

This study shows that overexpressing OsAnn5 in rice enhances tolerance to abiotic stresses by improving ROS scavenging and antioxidant enzyme balance in transgenic tobacco and E. coli.