Author

E. V. K. Ledger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2

Frequent Co-Authors

A. M. Edwards· 3 shared V. Pader· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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3 shared papersMicrobiology

A. M. Edwards

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3 papers

Recent·Most cited

Host-induced cell wall remodelling impairs opsonophagocytosis of Staphylococcus aureus by neutrophils

E. V. K. Ledger, A. M. Edwards

This study shows that S. aureus adapts to the host by thickening its cell wall, reducing opsonin exposure and impairing neutrophil phagocytosis and killing.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

Growth arrest of Staphylococcus aureus induces daptomycin tolerance via cell wall remodelling

E. V. K. Ledger, A. M. Edwards

This study shows that growth arrest of S. aureus increases daptomycin tolerance through cell wall remodelling, not just passive metabolic inactivity.

bioRxiv · Aug 10, 2022Microbiology

Enterococcus faecalis and pathogenic streptococci inactivate daptomycin by releasing phospholipids

E. V. K. Ledger, V. Pader, A. M. Edwards

This study shows that Enterococcus faecalis and other Gram-positive bacteria release phospholipids to inactivate daptomycin, reducing the antibiotic's effectiveness.

bioRxiv · Jun 14, 2017Microbiology