Topological defects govern mesenchymal condensations, offering a morphology-based tool to predict cartilage differentiation
E. Makhija, Y. Zheng, J. Wang, H. R. Leong, R. B. Othman, E. X. Ng, E. H. Lee, L. Tucker-Kellogg, Y. H. Lee, H. Yu, Z. Poon, K. J. Van Vliet
The paper shows that topological defects in cellular swirl patterns predict cartilage differentiation potential of mesenchymal stromal cells.
bioRxiv · May 30, 2022Biophysics