Y. H. Lee

Anti-muscle Atrophy Effects of Lactobacillus reuteri ATG-F4 and Its Impact on Intestinal Microbiota and Metabolites: Implications for Prophylaxis and Therapy

This study shows that Lactobacillus reuteri ATG-F4 reduces muscle atrophy by altering gut microbiota and metabolites, with anti-inflammatory effects.

High-density microbioreactor process designed for automated point-of-care manufacturing of CAR T cells

This paper introduces a high-density microbioreactor for automated CAR T cell manufacturing, achieving clinical dose levels in a small footprint with comparable functional attributes to traditional methods.

Topological defects govern mesenchymal condensations, offering a morphology-based tool to predict cartilage differentiation

The paper shows that topological defects in cellular swirl patterns predict cartilage differentiation potential of mesenchymal stromal cells.

Peritoneal autoantibody landscape in endometriosis

The paper profiles autoantibodies in peritoneal fluids of women with endometriosis, identifying significant autoantibody prevalence and associations with infertility and disease mechanisms.

Little skate genome exposes the gene regulatory mechanisms underlying the evolution of vertebrate locomotion

The paper generates a high-quality little skate genome and analyzes motor neuron gene regulation across species to identify conserved and divergent mechanisms in vertebrate locomotion evolution.

Clinical and immunological signatures of severe COVID-19 in previously healthy patients with clonal hematopoiesis

This study identifies clonal hematopoiesis as an independent risk factor for severe COVID-19 in previously healthy patients, revealing distinct immunological and epigenetic signatures.

Follicular fluid metabolome and cytokinome profiles in poor ovarian responders and the impact of dehydroepiandrosterone supplementation

This study examines the metabolome and cytokinome of follicular fluid in poor ovarian responders with and without DHEA supplementation, finding significant differences in metabolites and cytokines between groups.

Autocrine Signaling by Receptor Tyrosine Kinases in Urothelial Carcinoma of the Bladder

The paper identifies oncogenic alterations in receptor tyrosine kinases (TKs) and their association with poor survival in bladder cancer patients.

Regression of Human Breast Carcinoma in Nude Mice After Adsflt Gene Therapy is Mediated by Tumor Vascular Endothelial Cell Apoptosis

This study shows that Adsflt gene therapy reduces tumor volume and vascular density in breast cancer models by inducing vascular endothelial cell apoptosis.

Clearance of senescent decidual cells by uterine natural killer cells drives endometrial remodeling during the window of implantation