Mechanisms of action and synergies of a novel lipid IVA biosynthesis inhibitor
Emma R. Holden, Muhammad Yasir, A. Keith Turner, Mark Alexander Webber, Ian G. Charles, Ed Siegwart, Tony M. Raynham, Ajay Mistry, John George, Matthew W. Gilmour
This study identifies the target pathway of a novel antimicrobial compound and discovers synergies with existing antibiotics using genome-wide screening in Gram-negative bacteria.
bioRxiv · Sep 15, 2023 · PreprintMolecular Biology