Cancer BiologyPLoS GeneticsPeer-reviewed
A tumor-suppressive role of the PRC1 Polycomb epigenetic complex in the maintenance of adult Drosophila intestinal stem cell identity
Aurélia Joly, Ana-Maria Popmihaylova, Corinne Rancurel…·Raphaël Rousset
This paper shows that PRC1 suppresses tumor formation in Drosophila intestinal stem cells by maintaining their identity, and identifies immune pathways that limit tumor growth.