Absolute Quantification of Lysosomal Proteins by Multiple Reaction Monitoring Mass Spectrometry and QconCAT Protein Standards
Peter Mosen, Biswajit Moharana, Sofía Fajardo‐Callejón, Edgar Kaade, Norbert Rösel, Maryam Omidi, Roman Sakson, Thomas Ruppert, Sandra Pohl, Volkmar Gieselmann, Dominic Winter
The paper develops a mass spectrometry-based method to absolutely quantify lysosomal proteins in mouse cells, revealing expression dynamics and subcellular distribution differences.
bioRxiv · Jan 9, 2025 · PreprintMolecular Biology