Molecular BiologybioRxivPreprint
A genome-wide screen identifies SCAI as a modulator of the UV-induced replicative stress response in human cells
Jean-François Lemay, Edlie St-Hilaire, Sari Gezzar-Dandashi…·Hugo Würtele
The paper identifies SCAI as a novel regulator that modulates the UV-induced replicative stress response by inhibiting EXO1 activity and preventing excessive RPA-ssDNA accumulation.
DOI 10.1101/2022.01.17.476707