Loss of Mitochondrial Respiratory Capacity Reshapes Myeloid Cell Function during Mycobacterium tuberculosis infection
Eduardo L Martinez, Cory J. Mabry, Aja K. Coleman, Morgan S. Osborne, Joshua D. Simmons, Stacy Hahn, Jessica B. Huskey, Kaitlyn S. Armijo, Taylor Newbolt, Jacob R Davis, Lianna Zhou, Spyros A. Kalams, Denis Mogilenko, Kristin L. Patrick, Robert O. Watson
The paper shows that reduced mitochondrial respiratory capacity in myeloid cells during Mtb infection impairs immune function and Mtb control, with similar findings in human data.
bioRxiv · Sep 8, 2026 · PreprintImmunology