Author

Jacob R Davis

Texas A&M Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Aja K. ColemaniD· 2 shared Kristin L. PatrickiD· 2 shared Robert O. WatsoniD· 2 shared Chi Gidley WeindeliD· 1 shared Cory J. MabryiD· 1 shared Denis MogilenkoiD· 1 shared Eduardo L Martinez· 1 shared Jessica B. Huskey· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Aja K. ColemanORCID

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Author profile →

2 papers

Recent·Most cited

Loss of Mitochondrial Respiratory Capacity Reshapes Myeloid Cell Function during Mycobacterium tuberculosis infection

Eduardo L Martinez, Cory J. Mabry, Aja K. Coleman, Morgan S. Osborne, Joshua D. Simmons, Stacy Hahn, Jessica B. Huskey, Kaitlyn S. Armijo, Taylor Newbolt, Jacob R Davis, Lianna Zhou, Spyros A. Kalams, Denis Mogilenko, Kristin L. Patrick, Robert O. Watson

The paper shows that reduced mitochondrial respiratory capacity in myeloid cells during Mtb infection impairs immune function and Mtb control, with similar findings in human data.

bioRxiv · Sep 8, 2026 · PreprintImmunology

LRRK2 kinase activity restricts NRF2-dependent mitochondrial protection in microglia

Chi Gidley Weindel, Aja K. Coleman, Lily M Ellzey, Sandeep Kumar, Sara L Chaisson, Jacob R Davis, Kristin L. Patrick, Robert O. Watson

This study shows that LRRK2 kinase activity in microglia restricts NRF2-dependent mitochondrial protection, contrasting with its role in peripheral macrophages.

The Journal of Immunology · Sep 4, 2025Peer-reviewedImmunology